Benadryl Dosage Calculator for Dogs
Calculate safe dosage for your pet
Recommended Dosage
Important: Always consult your veterinarian before giving any medication to your pet.
About Benadryl for Dogs
Benadryl (diphenhydramine) is an antihistamine that can be used for dogs to treat allergies, motion sickness, and mild anxiety.
Safety Information
- Standard dosage is 1 mg per pound of body weight (2.2 mg per kg)
- Typically given every 8-12 hours as needed
- Not recommended for dogs with certain health conditions
- Avoid Benadryl with added decongestants
- Watch for side effects like drowsiness or dry mouth
When to Use
- Seasonal allergies
- Itching and skin irritation
- Mild allergic reactions
- Motion sickness prevention
- Mild anxiety situations
Warnings
Do not use Benadryl for dogs without consulting your veterinarian, especially if your dog has glaucoma, heart disease, high blood pressure, or is pregnant. Always use plain Benadryl (diphenhydramine only) without additional active ingredients.
Calculate the safe Benadryl dosage for your dog by weight. Get vet-approved guidelines for allergies, anxiety & motion sickness. Includes mg/kg chart.
How to Use the Benadryl Dosage Calculator for Dogs
This tool helps you calculate a safe dosage of Benadryl (diphenhydramine) for your dog based on their weight and specific needs.
Step-by-Step Instructions:
- Enter Your Dog's Weight
- Type your dog's weight in the "Dog's Weight" field
- Select whether the weight is in pounds (lbs) or kilograms (kg)
- Select Benadryl Strength
- Choose the strength of Benadryl you have:
- 25 mg (standard tablet)
- 50 mg (extra strength)
- Choose the strength of Benadryl you have:
- Choose the Purpose
- Select why you're giving Benadryl:
- Allergy Relief (for itching, seasonal allergies)
- Motion Sickness (for car rides/travel)
- Mild Anxiety (for stressful situations)
- Select why you're giving Benadryl:
- Calculate the Dosage
- Click the "Calculate Dosage" button
- View the Results
- The calculator will show:
- Recommended dosage in milligrams
- How many tablets to give
- How often to administer it
- Specific advice for your dog's condition
- The calculator will show:
Important Safety Notes:
- Always consult your veterinarian before giving any medication to your pet
- Never use Benadryl with added decongestants or other active ingredients
- The standard dosage is approximately 1 mg per pound of body weight (2.2 mg per kg)
- Watch for side effects like drowsiness or dry mouth
- Do not use for dogs with certain health conditions without veterinary approval
The calculator also includes helpful information about when to use Benadryl for dogs and important safety warnings. Be sure to read this information before administering any medication to your pet.
Remember that this tool provides general guidelines only and is not a substitute for professional veterinary advice.

Frequently Asked Questions (FAQ)
1. Is Benadryl safe for dogs?
✅ Yes, in proper doses.
- The active ingredient (diphenhydramine) is generally safe for dogs when dosed correctly.
- Avoid formulas with added decongestants, alcohol, or xylitol (toxic to dogs).
2. How much Benadryl can I give my dog?
- Standard dosage: 1 mg per pound (2.2 mg per kg) of body weight.
- Example: A 25-lb dog gets 25 mg (one 25 mg tablet).
- Max dosage: Typically 50 mg per dose (even for large dogs).
3. How often can I give Benadryl to my dog?
- Every 8–12 hours for allergies/anxiety.
- For motion sickness: Give 30–60 mins before travel (once per trip).
4. What are the side effects?
- Common: Drowsiness, dry mouth, mild digestive upset.
- Stop use and call a vet if: Agitation, rapid heartbeat, seizures, or difficulty breathing.
5. Can I use children’s liquid Benadryl?
- Yes, but check the concentration!
- Most children’s formulas are 12.5 mg per 5 mL.
- Example: A 10-lb dog needs 10 mg (~4 mL of liquid).
6. When should I not give Benadryl to my dog?
- ❌ If your dog has:
- Glaucoma
- Heart disease
- High blood pressure
- Pregnancy
- A history of seizures
7. How long does it take to work?
- 30–60 minutes for effects to begin.
- Lasts 8–12 hours (varies by dog).
8. My dog is very small (under 10 lbs). Is Benadryl safe?
- Proceed with caution! Tiny dogs are more sensitive.
- Ask your vet about half or quarter tablets or liquid dosing.
9. Can I use this calculator for cats?
- No! Cats process Benadryl differently.
- Consult a vet before giving any medication to cats.
10. What if my dog overdoses?
- Symptoms: Extreme drowsiness, agitation, seizures, rapid heartbeat.
- Action: Call your vet or Pet Poison Helpline (855-764-7661) immediately.
Final Reminder
This tool provides general guidelines only. Always consult your veterinarian for personalized advice, especially for:
- Puppies/senior dogs
- Dogs with health conditions
- Long-term use
🐾 When in doubt, ask a vet!